The Role Of Diet And Vitamin B3 In The Treatment Of Seborrheic Dermatitis - A Case Report

Case Report

Abstract

Seborrheic dermatitis is a chronic inflammatory skin disorder with a multifactorial etiology involving genetic predisposition, immune dysregulation, stress, and nutritional deficiencies. Its recurrent nature often requires complementary approaches beyond standard therapy. Recent studies emphasize the contribution of nutrition, particularly vitamins of the B complex, to modulating inflammatory responses and supporting skin repair. Vitamin B3 (niacin) plays a key role in cellular metabolism through its coenzymes NAD⁺ and NADP⁺, which are essential for mitochondrial energy production, oxidative balance, and epidermal regeneration. This study investigates the relationship between niacin status, dietary factors, and disease remission in seborrheic dermatitis.

A 41-year-old patient with seborrheic dermatitis presented with erythematous, scaly lesions on the face, nasolabial and retroauricular folds, eyebrows, and scalp, accompanied by severe itching. Laboratory tests revealed marked vitamin B3 deficiency. The patient received conventional therapy combined with niacin supplementation (25 mg/day) and a nutrient-balanced diet for six weeks. Clinical improvement was observed, with reduced inflammation, decreased scaling, and diminished pruritus.

These findings suggest that incorporating vitamin B3 supplementation into standard treatment protocols may enhance therapeutic outcomes. In conclusion, a holistic management strategy for seborrheic dermatitis—integrating conventional dermatologic therapy with targeted nutritional support—can promote longer remission periods and improve quality of life. Further controlled studies are needed to confirm the clinical efficacy and optimal dosing of niacin in the management of inflammatory skin conditions.